Thermo Fisher Scientific Presents an Ion Chromatography Method for Determination of Voriconazole Related Compound F in Voriconazole
Thermo Fisher Scientific introduces a sensitive and accurate ion chromatography method for determining voriconazole related compound F in voriconazole.
- San Jose, CA (1888PressRelease) November 09, 2012 - Thermo Fisher Scientific is pleased to announce an ion chromatography (IC) method that meets all the requirements of the proposed U.S. Pharmacopeia monograph method for determining voriconazole related compound F in voriconazole. Application Note 1022: Determination of Voriconazole Related Compound F in Voriconazole Using IC demonstrates that this method is sensitive, repeatable, and accurate using the solvent-compatible anion-exchange column specified in the proposed monograph with chemically suppressed conductivity detection. Determination can be made in 5 mg/mL sample solutions containing as low as 0.002% voriconazole related compound F.
Voriconazole is a second-generation triazole antifungal approved by the U.S. Food and Drug Administration in 2002 for the treatment of invasive aspergilliosis and other serious fungal infections. Invasive aspergilliosis is a rapidly progressive and often fatal infection that occurs in severely immunosuppressed patients, recipients of bone marrow and organ transplants, and those undergoing chemotherapy.
This application and many others can be found at www.thermoscientific.com/dionex under the Documents tab.
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