Thermo Fisher Scientific Announces a New Approach that Surpasses PPRC Method for Analysis of Zanthoxylum Nitidum (Roxb.) DC
Thermo Fisher Scientific introduces a comprehensive HPLC method for the quality control analysis of Zanthoxylum nitidum (Roxb.) DC.
- San Jose, CA (1888PressRelease) November 17, 2012 - Thermo Fisher Scientific is pleased to announce an efficient and comprehensive high-performance liquid chromatography (HPLC) method for the quality control analysis of Zanthoxylum nitidum (Roxb.) DC and related products. Application Note 1008: Determination of Nitidine Chloride, Toddalolactone, and Chelerythrine Chloride by HPLC describes the use of HPLC to rapidly separate the three main active components of Zanthoxylum nitidum (Roxb.) DC: nitidine chloride, chelerythrine chloride, and toddalolactone. This approach is superior to both the Pharmacopeia of the People's Republic of China (PPRC) method that measures the active components of Zanthoxylum nitidum (Roxb.) DC using two different methodsHPLC and thin-layer chromatographyand a published HPLC method that requires a long separation time.
In this new method, the determination is performed an HPLC system controlled by function-rich chromatography software. A sulfonamide-embedded reversed-phase LC column delivers excellent peak shape for nitidine chloride and chelerythrine chloride, using an ammonium acetate buffer/acetonitrile mobile phase without triethylamine.
This application note and many others can be found at www.thermoscientific.com/dionex under the Documents tab.
About Thermo Fisher Scientific
Thermo Fisher Scientific Inc. is the world leader in serving science. Our mission is to enable our customers to make the world healthier, cleaner and safer. With revenues of $12 billion, we have approximately 39,000 employees and serve customers within pharmaceutical and biotech companies, hospitals and clinical diagnostic labs, universities, research institutions and government agencies, as well as in environmental and process control industries. We create value for our key stakeholders through three premier brands, Thermo Scientific, Fisher Scientific and Unity™ Lab Services, which offer a unique combination of innovative technologies, convenient purchasing options and a single solution for laboratory operations management. Our products and services help our customers solve complex analytical challenges, improve patient diagnostics and increase laboratory productivity. Visit www.thermofisher.com.
All trademarks are the property of Thermo Fisher Scientific Inc. and its subsidiaries.
Chromatography
Social Media Contact Information
Sonya Pelia
1214 Oakmead Parkway
Sunnyvale, CA 94085 USA
Phone: +1 408 481 4172
sonya.pelia ( @ ) thermofisher dot com
###
space
space
Satisfied Users & 
Approved Press Releases
Print
Email
Report Spam