Roche and UCB to share case studies on Immunotoxins for Solid Tumour Therapy, Immunological Tolerance and Peptide Immunotherapy

SMi's 2nd annual Immunogenicity conference, taking place on 29-30 June 2015 in London, will help you further your understanding and modulate immunity in therapeutics. End Quote

(1888PressRelease) June 03, 2015 - Biopharmaceuticals (BPs) represent a rapidly growing class of approved and investigational drug therapies that is contributing significantly to advancing treatment in multiple disease areas, including inflammatory and autoimmune diseases, genetic deficiencies, and cancer. Unfortunately, unwanted immunogenic responses to BPs, in particular those affecting clinical safety or efficacy, remain among the most common negative effects associated with this important class of drugs. To manage and reduce risk of unwanted immunogenicity, diverse communities of clinicians, pharmaceutical industry, and academic scientists are involved in: interpretation and management of clinical and biological outcomes of BP immunogenicity, improvement of methods for describing, predicting and mitigating immunogenicity risk, and elucidation of underlying causes.

(Source: 'Standardizing terms, definitions and concepts for describing and interpreting unwanted immunogenicity of biopharmaceuticals: Recommendations of the innovative medicines initiative ABIRISK consortium', 8 May 2015, NCBI)

Against this backdrop, SMi's 2nd annual Immunogenicity conference will provide the ideal platform for the pharmaceutical industry, clinicians and academic scientists to align concepts and practices related to immunogenicity. The two-day conference programme will feature an array of case study driven presentations delivered by leading drug development teams, bioanalytical experts, and academics from companies including Apitope International NV, EpiVax, Inc, Roche Innovation Center Penzberg, Swedish Orphan Biovitrum and more.

Unique perspectives will be shared on:
• Immunogenicity challenges in biologics development
• Tolerance induction techniques
• The latest in pre-clinical models
• Neutralising antibody assay best practice
• Updates on the ABIRISK project

Speaker Panel includes:
• Annie De Groot, CEO and CSO, EpiVax, Inc.
• Sandra Garcês, Rheumatologist Consultant and Researcher, Garcia de Orta's Hospital
• David Wraith, Chief Scientific Officer and Founder, Apitope International NV
• Margareta Wikén, Bioanalytical Manager, Swedish Orphan Biovitrum
• Morten Nielsen, Associate Professor, The Technical University of Denmark
• Gerhard Niederfellner, Head of Tumour Cell Biology, Pharma Research & Early Development, Roche Innovation Center Penzberg
• Chloé Ackaert, Postdoctoral Researcher, Cellular and Molecular Immunology, Free University of Brussels

To view the full speaker line-up and conference programme, visit http://www.immuno.co.uk/1888pressrelease

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