Probiotics &Prebiotics May Hold The Key To Youthful Aging In Older Subjects
In April 2022, amedical research team from Pamplona, Spain, published the first meta-analysis of probiotics and prebiotics on those over 65 years, citing that probiotics and prebiotics represent an excellent opportunity to manage the process of aging and offer promise for health prevention in old adults.
- (1888PressRelease) August 11, 2022 - Whanganui, New Zealand - We knows from the research conducted over the past 20 years that probiotics and prebiotics (the food that probiotics and healthy bacteria feed on) can significantly benefit human health.
However, despite these advances, we still lack knowledge and understanding of how probiotics and prebiotics impact our health at different stages of our lifespan.
In April 2022, a research team from Hospital Universitario de Navarra in Pamplona, Spain, published a meta-analysis of 10 previously published randomized clinical trials of probiotics and prebiotics on those over the age of 65 years.
They examined how these 10 clinical studies impacted nutritional, metabolic, and immune functions in older subjects. They then used the combined data from the studies to improve the statistical power over what would otherwise be achieved from just a single clinical study.
After reviewing and analyzing the combined data from the 10 clinical studies, the research team was able to find evidence that probiotics and prebiotics improved the following areas of health in older subjects:
• Improved blood glucose levels and glucose metabolism
• Improved blood lipid profile with lowered triglyceride levels
• Reduced body mass index
• Enhanced cognitive function
• Reduced frailty as measured by exhaustion and handgrip strength
• Improved bowel function and motility (i.e., regularity)
• Enhanced immune response with a focus on reduced inflammation.
One of the most exciting and potentially significant areas of health impacted by probiotics and prebiotics was how they helped control inflammation in the body. Currently, a great deal of research is centered around inflammation and aging. It’s a new framework for research that examines the immune–metabolic connection for age-related diseases, called“inflammaging.”
What is compelling about what the Spanish team has uncovered in their review of the 10 clinical trials is that probiotics and prebiotics provoked the release of powerful anti-inflammatory cytokines within the body called IL-10 (interleukin-10). They found a corresponding drop in the pro-inflammatory cytokine called IL-1ß(interleukin-1ß), considered the master switch for inflammation in the body. They also found a reduction in another pro-inflammatory molecule produced by the body, called tumor necrosis factor-alpha (TNF-α). Finally, it was shown that there was a significant decrease in low-grade inflammation in those subjects taking probiotics, as measured by blood levels of c-reactive protein (CRP).
This type of study is important because several earlier studies on the composition of human gut bacteria indicate that older subjects have patterns of bacterial diversity and composition that are significantly different from younger subjects. Studies also reported that there exists a wider variability in the composition of gut bacteria between older subjects, leading some researchers to speculate on the existence of a profile or composition of gut bacteria that significantly slows the aging process and promotes anti-aging benefits. In contrast, another profile actively accelerates the aging process and promotes fragility in older people.
Reference: https://doi.org/10.1016/j.exger.2022.111809
Probiotics, when consumed regularly and in sufficient amounts, support and strengthen our natural population of gut bacteria and confer health benefits when they are consumed.
The evidence clearly shows that the composition of our gut bacteria is one of these important environmental factors, capable of turning our genes on or off, depending on the types of bacteria present.
With the publication of this study in April 2022, the evidence is more vital than ever that having a healthy and diverse population of gut bacteria as we get older is an excellent predictor of healthy aging. The more diverse, the better because we are more protected from illness, and we become more nutritionally healthy.
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If you want an excellent probiotic and probiotic combination that delivers 60 billion CFUs (live organisms) per serving along with 18 proven probiotic strains go to FREZZOR.com
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