New Hydrophobic Interaction Column Offers Additional Selectivity for Separating Monoclonal Antibodies or Antibody-drug Conjugates

Thermo Fisher Scientific has developed a liquid chromatography column able to separate different monoclonal antibodies than existing columns, providing useful new capabilities for biopharmaceutical research. End Quote

(1888PressRelease) August 21, 2014 - SAN JOSE, Calif. - Many laboratories analyzing monoclonal antibodies (mAb) regularly encounter situations where they need alternative hydrophobic interaction chromatography (HIC) selectivity. Thermo Fisher Scientific has developed new column chemistry that separates many more of these challenging mAbs, antibody-drug conjugates (ADCs) and proteins.

The Thermo Scientific MAbPac HIC-10 HPLC column has been demonstrated to provide selectivity that is different from other commercial HIC columns, including separating many native mAbs, fragments, aggregates, oxidation variants, PEGylated mAbs and ADC.

The column's proprietary chemistry is designed to provide the new selectivity in a high-resolution column with excellent biocompatibility and high recovery. The column is compatible with organic solvent and aqueous mobile phase. It is designed for rugged stability and very low carry-over.

"MAbs are the most successful and prominent class of biotherapeutics," said Ilze Birznieks, product line manager, biocolumns, Thermo Fisher Scientific. "HIC is a popular technique for separating these biomolecules, but researchers have been continually asking for alternative selectivity. This new column responds to these customer demands."

For more information, please visit www.thermoscientific.com/mabpacHIC.

About Thermo Fisher Scientific
Thermo Fisher Scientific Inc. is the world leader in serving science, with revenues of $17 billion and 50,000 employees in 50 countries. Our mission is to enable our customers to make the world healthier, cleaner and safer. We help our customers accelerate life sciences research, solve complex analytical challenges, improve patient diagnostics and increase laboratory productivity. Through our four premier brands - Thermo Scientific, Life Technologies, Fisher Scientific and Unity Lab Services - we offer an unmatched combination of innovative technologies, purchasing convenience and comprehensive support. For more information, please visit www.thermofisher.com.

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