New DXL Calscan study presented at Osteologie 2009 in Frankfurt

Peripheral bone densitometer DXL Calscan shown to be "clearly more effective" than iDXA scans of the spine in identifying patients with clinical osteoporosis and verified vertebral fractures. End Quote

Everyone should have the right to know their bone status with a quick and reliable DXA scan.

(1888PressRelease) March 21, 2009 - The VINFORCE study team from the Medical University of Vienna made an important oral presentation of their study results at the prestigious Osteologie 2009 Congress in Frankfurt. The study team is led by Prof. Heinrich Resch and Dr. Christian Muschitz. The study compared the ability of calcaneal scans using DXL Calscan to hip and spine scans using the iDXA device to identify 131 patients verified by x-ray to have a combined total of 390 vertebral fractures, i.e. clinical osteoporosis. A control group of 399 patients without the condition allowed area under receiver operating curves (AUC) to be calculated and compared for the respective scanning sites and devices.

Results showed that the DXL Calscan scans of the calcaneus (AUC=0.70) are as effective as iDXA scans of the hip (AUC=0.69), and clearly more effective than iDXA scans of the spine (AUC=0.62), to discriminate between patients with clinical osteoporosis and the control group. In addition, when using the lowest iDXA T-score from the hip and spine results as suggested by most national osteoporosis guidelines, the AUC results became less predictive of clinical osteoporosis than if femur neck results only were used. The mean T-score for osteoporotic fracture patients was -2.67 for DXL scans, which is an osteoporotic result as expected. However the mean values for osteoporotic fracture patients scanned by iDXA at total hip (-1.80), femur neck (-2.00) and spine (-2.04) unexpectedly showed non-osteoporotic results.

The conclusion of the presentation stated that DXL Calscan can be used as an effective diagnostic tool in clinical practice. The VINFORCE team is planning submission of the full scientific article to an international medical journal later this year.

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