BOC Science Launched ADC Linker Design and Synthesis Service
BOC Science, a leading chemicals supplier, launched its cutting-edge linker design and synthesis service.
- Binghamton, NY (1888PressRelease) May 01, 2024 - BOC Science, a leading chemicals supplier, launched its cutting-edge linker design and synthesis service.
In the realm of ADC design, the selection of linkers and release strategies plays a pivotal role in achieving a delicate balance between drug efficacy, safety, circulation stability, target selectivity, and cost efficiency. Despite significant strides in linker design over the past decade, several formidable hurdles persist.
Chief among these challenges is the need for linkers to mirror the stability of antibodies at physiologically relevant pH levels to prevent premature drug release, given the antibodies' extended half-lives spanning multiple days. Additionally, the attachment of linkers and antibiotic agents to antibodies must exert minimal adverse effects on the biological properties and stability of the antibodies themselves.
Leveraging a profound understanding of the pivotal role of linkers in ADC development, coupled with years of expertise in compound synthesis, BOC Science launching its ADC linker design and synthesis service.
We have already accumulated some successful cases, such as one client who had unclear requirements for the linker of the compound they needed to couple. We provided the client with professional coupling technology solutions, along with appropriate product selection schemes, successfully solving the linker issue for the client and helping them smoothly complete their research project," said a spokesperson for BOC Science.
In the eyes of the spokesperson at BOC Science, the advantages of BOC Science are very apparent. She stated, "BOC Science has dozens of production lines that comply with GMP standards, equipped with over 100 reactors ranging in capacity from 20L to 2000L, suitable for reactions from grams to tons. We can provide professional advice and support for the design, synthesis, development, manufacturing, and cutting conditions optimization of linkers. We can scale up the synthesis of ADC linkers to meet customers' clinical and commercial development needs, from milligrams to kilograms or even larger scales.”
About BOC Science:
BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies.
For more information, please visit our website: www.bocsci.com
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